Structure based discovery of small molecule suppressors targeting bacterial lysozyme inhibitors.

Voet, Arnout; Callewaert, Lien; Ulens, Tim; Vanderkelen, Lise; Vanherreweghe, Joris M; Michiels, Chris W; De Maeyer, Marc

Voet, Arnout; Callewaert, Lien; Ulens, Tim; Vanderkelen, Lise; Vanherreweghe, Joris M; Michiels, Chris W; De Maeyer, Marc.

Affiliation

Voet A; Laboratory for Biomolecular Modelling and BioMacS, Katholieke Universiteit Leuven, Celestijnenlaan 200G bus 2403, 3001 Heverlee, Leuven, Belgium. arnout.voet@fys.kuleuven.be

Biochem Biophys Res Commun ; 405(4): 527-32, 2011 Feb 25.

Article in En | MEDLINE | ID: mdl-21256115

Subject(s)

Anti-Bacterial Agents/chemistry; Bacterial Proteins/antagonists & inhibitors; Drug Discovery/methods; Models, Molecular; Muramidase/antagonists & inhibitors; Salmonella typhimurium/metabolism; Amino Acid Sequence; Anti-Bacterial Agents/isolation & purification; Anti-Bacterial Agents/pharmacology; Bacterial Proteins/chemistry; Bacterial Proteins/metabolism; Computer Simulation; Molecular Sequence Data; Muramidase/chemistry; Muramidase/metabolism; Protein Conformation; Recombinant Proteins/antagonists & inhibitors; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Salmonella typhimurium/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salmonella typhimurium / Bacterial Proteins / Models, Molecular / Muramidase / Drug Discovery / Anti-Bacterial Agents Language: En Journal: Biochem Biophys Res Commun Year: 2011 Type: Article Affiliation country: Belgium

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