Isolation rearing-induced reduction of brain 5&#945;-reductase expression: relevance to dopaminergic impairments.

Bortolato, Marco; Devoto, Paola; Roncada, Paola; Frau, Roberto; Flore, Giovanna; Saba, Pierluigi; Pistritto, Giuseppa; Soggiu, Alessio; Pisanu, Salvatore; Zappala, Agata; Ristaldi, Maria Serafina; Tattoli, Maria; Cuomo, Vincenzo; Marrosu, Francesco; Barbaccia, Maria Luisa

Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments.

Bortolato, Marco; Devoto, Paola; Roncada, Paola; Frau, Roberto; Flore, Giovanna; Saba, Pierluigi; Pistritto, Giuseppa; Soggiu, Alessio; Pisanu, Salvatore; Zappala, Agata; Ristaldi, Maria Serafina; Tattoli, Maria; Cuomo, Vincenzo; Marrosu, Francesco; Barbaccia, Maria Luisa.

Affiliation

Bortolato M; Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90031, USA. bortolat@usc.edu

Neuropharmacology ; 60(7-8): 1301-8, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21256141

Subject(s)

Behavior, Animal/physiology; Brain Chemistry/drug effects; Cholestenone 5 alpha-Reductase/biosynthesis; Dopamine/metabolism; Social Isolation; 3,4-Dihydroxyphenylacetic Acid/analysis; 3,4-Dihydroxyphenylacetic Acid/metabolism; 5-alpha Reductase Inhibitors/pharmacology; Animals; Brain/metabolism; Desoxycorticosterone/analogs & derivatives; Desoxycorticosterone/blood; Desoxycorticosterone/metabolism; Finasteride/pharmacology; Male; Nucleus Accumbens/metabolism; Prefrontal Cortex/metabolism; Pregnanolone/blood; Pregnanolone/metabolism; Rats; Rats, Sprague-Dawley

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Social Isolation / Behavior, Animal / Brain Chemistry / Dopamine / Cholestenone 5 alpha-Reductase Limits: Animals Language: En Journal: Neuropharmacology Year: 2011 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google