Evaluation of the profibrinolytic properties of an anti-TAFI monoclonal antibody in a mouse thromboembolism model.

Vercauteren, Ellen; Emmerechts, Jan; Peeters, Miet; Hoylaerts, Marc F; Declerck, Paul J; Gils, Ann

Vercauteren, Ellen; Emmerechts, Jan; Peeters, Miet; Hoylaerts, Marc F; Declerck, Paul J; Gils, Ann.

Affiliation

Vercauteren E; Laboratory for Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium.

Blood ; 117(17): 4615-22, 2011 Apr 28.

Article in En | MEDLINE | ID: mdl-21343611

Subject(s)

Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/pharmacology; Carboxypeptidase B2/immunology; Fibrinolysis/immunology; Thromboembolism/therapy; Animals; Antibody Affinity/immunology; Antithrombin III/immunology; Carboxypeptidase B2/metabolism; Cross Reactions/immunology; Disease Models, Animal; Humans; In Vitro Techniques; Lung/blood supply; Lung/immunology; Mice; Mice, Mutant Strains; Peptide Hydrolases/immunology; Species Specificity; Thromboembolism/immunology; Thromboembolism/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thromboembolism / Carboxypeptidase B2 / Fibrinolysis / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: Belgium

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