Adipose-derived stem cells accelerate neovascularization in ischaemic diabetic skin flap via expression of hypoxia-inducible factor-1&#945;.

Gao, Weicheng; Qiao, Xing; Ma, Shaolin; Cui, Lei

Adipose-derived stem cells accelerate neovascularization in ischaemic diabetic skin flap via expression of hypoxia-inducible factor-1α.

Gao, Weicheng; Qiao, Xing; Ma, Shaolin; Cui, Lei.

Affiliation

Gao W; Department of Plastic Surgery, 1st Teaching Hospital of Xinjiang Medical University, China.

J Cell Mol Med ; 15(12): 2575-85, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21435171

Subject(s)

Adipocytes/cytology; Diabetes Mellitus, Experimental/pathology; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Ischemia/pathology; Neovascularization, Pathologic; Stem Cells/cytology; Surgical Flaps/blood supply; Adipocytes/metabolism; Adult; Animals; Apoptosis; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Experimental/metabolism; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Graft Survival; Humans; Hypoxia/metabolism; Immunoenzyme Techniques; Ischemia/metabolism; Male; Mice; Mice, Inbred BALB C; Skin Transplantation; Stem Cells/metabolism; Surgical Flaps/physiology; Vascular Endothelial Growth Factor A/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Surgical Flaps / Adipocytes / Diabetes Mellitus, Experimental / Hypoxia-Inducible Factor 1, alpha Subunit / Ischemia / Neovascularization, Pathologic Limits: Adult / Animals / Humans / Male Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2011 Type: Article Affiliation country: China

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