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Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
Dash, Rupesh; Azab, Belal; Quinn, Bridget A; Shen, Xuening; Wang, Xiang-Yang; Das, Swadesh K; Rahmani, Mohamed; Wei, Jun; Hedvat, Michael; Dent, Paul; Dmitriev, Igor P; Curiel, David T; Grant, Steven; Wu, Bainan; Stebbins, John L; Pellecchia, Maurizio; Reed, John C; Sarkar, Devanand; Fisher, Paul B.
Affiliation
  • Dash R; Department of Human and Molecular Genetics, Virginia Commonwealth University Institute of Molecular Medicine, and Virginia Commonwealth University Massey Cancer Center, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.
Proc Natl Acad Sci U S A ; 108(21): 8785-90, 2011 May 24.
Article in En | MEDLINE | ID: mdl-21555592

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Gossypol / Genetic Therapy / Antineoplastic Combined Chemotherapy Protocols / Apoptosis / Proto-Oncogene Proteins c-bcl-2 Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2011 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Gossypol / Genetic Therapy / Antineoplastic Combined Chemotherapy Protocols / Apoptosis / Proto-Oncogene Proteins c-bcl-2 Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2011 Type: Article Affiliation country: United States