A sphingosine 1-phosphate 1 receptor agonist modulates brain death-induced neurogenic pulmonary injury.

Sammani, Saad; Park, Ki-Sung; Zaidi, Syed R; Mathew, Biji; Wang, Ting; Huang, Yong; Zhou, Tong; Lussier, Yves A; Husain, Aliya N; Moreno-Vinasco, Liliana; Vigneswaran, Wickii T; Garcia, Joe G N

Sammani, Saad; Park, Ki-Sung; Zaidi, Syed R; Mathew, Biji; Wang, Ting; Huang, Yong; Zhou, Tong; Lussier, Yves A; Husain, Aliya N; Moreno-Vinasco, Liliana; Vigneswaran, Wickii T; Garcia, Joe G N.

Affiliation

Sammani S; Section of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois at Chicago, 60612, USA.

Am J Respir Cell Mol Biol ; 45(5): 1022-7, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21617203

Subject(s)

Brain Death/metabolism; Lung Injury/drug therapy; Oxadiazoles/pharmacology; Pulmonary Edema/drug therapy; Receptors, Lysosphingolipid/agonists; Thiophenes/pharmacology; Animals; Bronchoalveolar Lavage Fluid/chemistry; Capillary Permeability/drug effects; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Gene Expression/drug effects; Lung/drug effects; Lung/metabolism; Lung Injury/etiology; Lung Injury/pathology; Male; Pulmonary Edema/complications; Pulmonary Edema/etiology; Rats; Rats, Sprague-Dawley; Receptors, CCR2/genetics; Receptors, CCR2/metabolism; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism; Up-Regulation/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxadiazoles / Pulmonary Edema / Thiophenes / Brain Death / Receptors, Lysosphingolipid / Lung Injury Type of study: Etiology_studies Limits: Animals Language: En Journal: Am J Respir Cell Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2011 Type: Article Affiliation country: United States

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