Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816.

Kim, Soo Young; Kang, Jamie J; Lee, Hyung Hoan; Kang, Jenny J; Kim, Bokyung; Kim, Chan-Gil; Park, Tae-Kyu; Kang, Hyun

Kim, Soo Young; Kang, Jamie J; Lee, Hyung Hoan; Kang, Jenny J; Kim, Bokyung; Kim, Chan-Gil; Park, Tae-Kyu; Kang, Hyun.

Affiliation

Kim SY; Department of Biological Sciences, Konkuk University, Seoul 143-701, Republic of Korea.

Biochem Biophys Res Commun ; 410(2): 224-8, 2011 Jul 01.

Article in En | MEDLINE | ID: mdl-21640708

Subject(s)

Aspartic Acid/genetics; Proto-Oncogene Proteins c-kit/genetics; Proto-Oncogene Proteins c-kit/metabolism; Amino Acid Sequence; Cell Membrane/enzymology; Enzyme Activation/genetics; Humans; Molecular Sequence Data; Phosphorylation; Point Mutation; Protein Multimerization; Protein Structure, Tertiary; Proto-Oncogene Mas; Proto-Oncogene Proteins c-kit/chemistry; Tyrosine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspartic Acid / Proto-Oncogene Proteins c-kit Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2011 Type: Article

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