Aberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancer.

Ling, Zhi-Qiang; Li, Pei; Ge, Ming-Hua; Hu, Fu-Jun; Fang, Xian-Hua; Dong, Zi-Min; Mao, Wei-Min

Ling, Zhi-Qiang; Li, Pei; Ge, Ming-Hua; Hu, Fu-Jun; Fang, Xian-Hua; Dong, Zi-Min; Mao, Wei-Min.

Affiliation

Ling ZQ; Zhejiang Cancer Research Institute, Zhejiang Province Cancer Hospital, Zhejiang Cancer Center, No. 38 Guangji Rd., Banshanqiao District, 310022, Hangzhou, People's Republic of China. lingzq@hotmail.com

Dig Dis Sci ; 56(10): 2992-3004, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21674174

Subject(s)

Carcinoma, Squamous Cell/diagnosis; Carcinoma, Squamous Cell/genetics; DNA Methylation/genetics; DNA Repair/genetics; DNA, Neoplasm/genetics; Esophageal Neoplasms/diagnosis; Esophageal Neoplasms/genetics; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/metabolism; Carcinoma, Squamous Cell/mortality; Case-Control Studies; CpG Islands/genetics; DNA Modification Methylases/genetics; DNA Modification Methylases/metabolism; DNA Repair Enzymes/genetics; DNA Repair Enzymes/metabolism; Esophageal Neoplasms/mortality; Esophagus/metabolism; Female; Humans; Kaplan-Meier Estimate; Male; MutL Protein Homolog 1; MutS Homolog 2 Protein/genetics; MutS Homolog 2 Protein/metabolism; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Predictive Value of Tests; Prognosis; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Neoplasm / Esophageal Neoplasms / Carcinoma, Squamous Cell / DNA Methylation / DNA Repair Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Dig Dis Sci Year: 2011 Type: Article

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