Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly.

Tsai, Connie Y; Ngo, Bryan; Tapadia, Anjali; Hsu, Pang-Hung; Wu, Guikai; Lee, Wen-Hwa

Tsai, Connie Y; Ngo, Bryan; Tapadia, Anjali; Hsu, Pang-Hung; Wu, Guikai; Lee, Wen-Hwa.

Affiliation

Tsai CY; Department of Biological Chemistry, University of California, Irvine, California 92697-4037, USA.

J Biol Chem ; 286(34): 30097-106, 2011 Aug 26.

Article in En | MEDLINE | ID: mdl-21705324

Subject(s)

Metaphase/physiology; Microtubule-Associated Proteins/metabolism; Microtubules/metabolism; Prophase/physiology; Protein Serine-Threonine Kinases/metabolism; Spindle Apparatus/metabolism; Aurora Kinases; Cell Line, Tumor; Humans; Microtubule-Associated Proteins/genetics; Microtubules/genetics; Mutation; Phosphorylation/physiology; Protein Serine-Threonine Kinases/genetics; Protein Structure, Tertiary; Spindle Apparatus/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prophase / Protein Serine-Threonine Kinases / Metaphase / Microtubule-Associated Proteins / Microtubules / Spindle Apparatus Limits: Humans Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: United States

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