Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeleton.

Rahman, Parvin; Huysmans, Richard D; Wiradjaja, Fenny; Gurung, Rajendra; Ooms, Lisa M; Sheffield, David A; Dyson, Jennifer M; Layton, Meredith J; Sriratana, Absorn; Takada, Hidetoshi; Tiganis, Tony; Mitchell, Christina A

Rahman, Parvin; Huysmans, Richard D; Wiradjaja, Fenny; Gurung, Rajendra; Ooms, Lisa M; Sheffield, David A; Dyson, Jennifer M; Layton, Meredith J; Sriratana, Absorn; Takada, Hidetoshi; Tiganis, Tony; Mitchell, Christina A.

Affiliation

Rahman P; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

J Biol Chem ; 286(34): 29758-70, 2011 Aug 26.

Article in En | MEDLINE | ID: mdl-21712384

Subject(s)

Actins/metabolism; Adaptor Proteins, Signal Transducing/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Phosphoric Monoester Hydrolases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction/physiology; Stress Fibers/metabolism; Actins/genetics; Adaptor Proteins, Signal Transducing/genetics; Animals; Cell Movement/physiology; Embryo, Mammalian/metabolism; Fibroblasts/metabolism; Focal Adhesions/genetics; Focal Adhesions/metabolism; Inositol Polyphosphate 5-Phosphatases; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases/genetics; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases/antagonists & inhibitors; Phosphoric Monoester Hydrolases/genetics; Proto-Oncogene Proteins c-akt/genetics; Pseudopodia/genetics; Pseudopodia/metabolism; Stress Fibers/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Actins / Phosphoric Monoester Hydrolases / Phosphatidylinositol 3-Kinases / Stress Fibers / Adaptor Proteins, Signal Transducing / Proto-Oncogene Proteins c-akt Limits: Animals Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: Australia

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