Crystal structure of the ß2 adrenergic receptor-Gs protein complex.

Rasmussen, Søren G F; DeVree, Brian T; Zou, Yaozhong; Kruse, Andrew C; Chung, Ka Young; Kobilka, Tong Sun; Thian, Foon Sun; Chae, Pil Seok; Pardon, Els; Calinski, Diane; Mathiesen, Jesper M; Shah, Syed T A; Lyons, Joseph A; Caffrey, Martin; Gellman, Samuel H; Steyaert, Jan; Skiniotis, Georgios; Weis, William I; Sunahara, Roger K; Kobilka, Brian K

Rasmussen, Søren G F; DeVree, Brian T; Zou, Yaozhong; Kruse, Andrew C; Chung, Ka Young; Kobilka, Tong Sun; Thian, Foon Sun; Chae, Pil Seok; Pardon, Els; Calinski, Diane; Mathiesen, Jesper M; Shah, Syed T A; Lyons, Joseph A; Caffrey, Martin; Gellman, Samuel H; Steyaert, Jan; Skiniotis, Georgios; Weis, William I; Sunahara, Roger K; Kobilka, Brian K.

Affiliation

Rasmussen SG; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature ; 477(7366): 549-55, 2011 Jul 19.

Article in En | MEDLINE | ID: mdl-21772288

Subject(s)

GTP-Binding Protein alpha Subunits, Gs/chemistry; GTP-Binding Protein alpha Subunits, Gs/metabolism; Receptors, Adrenergic, beta-2/chemistry; Receptors, Adrenergic, beta-2/metabolism; Adrenergic beta-2 Receptor Agonists/chemistry; Adrenergic beta-2 Receptor Agonists/metabolism; Animals; Catalytic Domain; Cattle; Crystallization; Crystallography, X-Ray; Enzyme Activation; Models, Molecular; Multiprotein Complexes/chemistry; Multiprotein Complexes/metabolism; Protein Binding; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Adrenergic, beta-2 / GTP-Binding Protein alpha Subunits, Gs Limits: Animals Language: En Journal: Nature Year: 2011 Type: Article Affiliation country: United States

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