Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load.

Day, Cheryl L; Abrahams, Deborah A; Lerumo, Lesedi; Janse van Rensburg, Esme; Stone, Lynnett; O'rie, Terrence; Pienaar, Bernadette; de Kock, Marwou; Kaplan, Gilla; Mahomed, Hassan; Dheda, Keertan; Hanekom, Willem A

Day, Cheryl L; Abrahams, Deborah A; Lerumo, Lesedi; Janse van Rensburg, Esme; Stone, Lynnett; O'rie, Terrence; Pienaar, Bernadette; de Kock, Marwou; Kaplan, Gilla; Mahomed, Hassan; Dheda, Keertan; Hanekom, Willem A.

Affiliation

Day CL; South African Tuberculosis Vaccine Initiative and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa. cheryl.day@uct.ac.za

J Immunol ; 187(5): 2222-32, 2011 Sep 01.

Article in En | MEDLINE | ID: mdl-21775682

Subject(s)

Bacterial Load; T-Lymphocyte Subsets/immunology; T-Lymphocytes/immunology; Tuberculosis/immunology; Tuberculosis/microbiology; Adolescent; Adult; Cell Proliferation; Cell Separation; Cytokines/biosynthesis; Disease Progression; Female; Flow Cytometry; Humans; Male; Middle Aged; Mycobacterium tuberculosis/immunology; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / T-Lymphocytes / T-Lymphocyte Subsets / Bacterial Load Type of study: Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: J Immunol Year: 2011 Type: Article Affiliation country: South Africa

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