The effect of formoterol on airway goblet cell hyperplasia and protein Muc5ac expression in asthmatic mice.

Tan, Y F; Zhang, W; Yang, L; Jiang, S P

Tan, Y F; Zhang, W; Yang, L; Jiang, S P.

Affiliation

Tan YF; Department of Respiratory Medicine, the Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Eur Rev Med Pharmacol Sci ; 15(7): 743-50, 2011 Jul.

Article in En | MEDLINE | ID: mdl-21780541

Subject(s)

Adrenergic beta-2 Receptor Agonists/pharmacology; Asthma/drug therapy; Bronchodilator Agents/pharmacology; Ethanolamines/pharmacology; Goblet Cells/drug effects; Lung/drug effects; Mucin 5AC/metabolism; Analysis of Variance; Animals; Asthma/genetics; Asthma/immunology; Asthma/metabolism; Asthma/pathology; Disease Models, Animal; Down-Regulation; Female; Formoterol Fumarate; Goblet Cells/immunology; Goblet Cells/metabolism; Goblet Cells/pathology; Hyperplasia; Immunohistochemistry; Lung/immunology; Lung/metabolism; Lung/pathology; Mice; Mice, Inbred BALB C; Mucin 5AC/genetics; Ovalbumin; RNA, Messenger/metabolism; Reverse Transcriptase Polymerase Chain Reaction

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Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Bronchodilator Agents / Goblet Cells / Ethanolamines / Mucin 5AC / Adrenergic beta-2 Receptor Agonists / Lung Limits: Animals Language: En Journal: Eur Rev Med Pharmacol Sci Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2011 Type: Article Affiliation country: China

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