Benzotriazoles and indazoles are scaffolds with biological activity against Entamoeba histolytica.

López-Vallejo, Fabian; Castillo, Rafael; Yépez-Mulia, Lilián; Medina-Franco, José L

López-Vallejo, Fabian; Castillo, Rafael; Yépez-Mulia, Lilián; Medina-Franco, José L.

Affiliation

López-Vallejo F; Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, FL 34987, USA. fvallejo@tpims.org

J Biomol Screen ; 16(8): 862-8, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21821786

Subject(s)

Amebicides/chemistry; Entamoeba histolytica/drug effects; Entamoebiasis/drug therapy; Indazoles/chemistry; Triazoles/chemistry; Amebicides/pharmacology; Amebicides/therapeutic use; Benzimidazoles/chemistry; Benzimidazoles/pharmacology; Benzimidazoles/therapeutic use; Databases, Factual; Entamoeba histolytica/growth & development; Entamoebiasis/microbiology; Humans; Indazoles/pharmacology; Indazoles/therapeutic use; Inhibitory Concentration 50; Metronidazole/chemistry; Metronidazole/pharmacology; Metronidazole/therapeutic use; Quantitative Structure-Activity Relationship; Small Molecule Libraries/chemistry; Small Molecule Libraries/pharmacology; Small Molecule Libraries/therapeutic use; Structure-Activity Relationship; Triazoles/pharmacology; Triazoles/therapeutic use

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazoles / Entamoeba histolytica / Entamoebiasis / Amebicides / Indazoles Limits: Humans Language: En Journal: J Biomol Screen Journal subject: BIOLOGIA MOLECULAR Year: 2011 Type: Article Affiliation country: United States

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