ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters.

Huang, Royston-Luke; Teo, Ziqiang; Chong, Han Chung; Zhu, Pengcheng; Tan, Ming Jie; Tan, Chek Kun; Lam, Chee Ren Ivan; Sng, Ming Keat; Leong, David Tai Wei; Tan, Suet Mien; Kersten, Sander; Ding, Jeak Ling; Li, Hoi Yeung; Tan, Nguan Soon

Huang, Royston-Luke; Teo, Ziqiang; Chong, Han Chung; Zhu, Pengcheng; Tan, Ming Jie; Tan, Chek Kun; Lam, Chee Ren Ivan; Sng, Ming Keat; Leong, David Tai Wei; Tan, Suet Mien; Kersten, Sander; Ding, Jeak Ling; Li, Hoi Yeung; Tan, Nguan Soon.

Affiliation

Huang RL; School of Biological Sciences, Nanyang Technological University, Singapore.

Blood ; 118(14): 3990-4002, 2011 Oct 06.

Article in En | MEDLINE | ID: mdl-21841165

Subject(s)

Angiopoietins/metabolism; Antigens, CD/metabolism; Cadherins/metabolism; Claudins/metabolism; Integrin alpha5beta1/metabolism; Angiopoietin-Like Protein 4; Angiopoietins/genetics; Animals; Capillary Permeability; Cells, Cultured; Claudin-5; Endothelial Cells/cytology; Endothelial Cells/metabolism; Endothelium, Vascular/cytology; Gene Expression Regulation, Neoplastic; Humans; Lung/pathology; Mice; Mice, Nude; Neoplasm Metastasis/pathology; Neoplasms/blood supply; Neoplasms/genetics; Neoplasms/metabolism; beta Catenin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antigens, CD / Cadherins / Integrin alpha5beta1 / Angiopoietins / Claudins Limits: Animals / Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: Singapore

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