Estrogen controls embryonic stem cell proliferation via store-operated calcium entry and the nuclear factor of activated T-cells (NFAT).

Wong, Chun-Kit; So, Wing-Yan; Law, Sau-Kwan; Leung, Fung-Ping; Yau, Ka-Long; Yao, Xiaoqiang; Huang, Yu; Li, Xiangdong; Tsang, Suk-Ying

Wong, Chun-Kit; So, Wing-Yan; Law, Sau-Kwan; Leung, Fung-Ping; Yau, Ka-Long; Yao, Xiaoqiang; Huang, Yu; Li, Xiangdong; Tsang, Suk-Ying.

Affiliation

Wong CK; School of Life Sciences, Chinese University of Hong Kong, Hong Kong, China.

J Cell Physiol ; 227(6): 2519-30, 2012 Jun.

Article in En | MEDLINE | ID: mdl-21898397

Subject(s)

Calcium Channels/metabolism; Calcium Signaling; Cell Proliferation; Embryonic Stem Cells/metabolism; Estradiol/metabolism; NFATC Transcription Factors/metabolism; Pluripotent Stem Cells/metabolism; Animals; Biomarkers/metabolism; Calcineurin/metabolism; Calcineurin Inhibitors; Calcium Channel Blockers/pharmacology; Calcium Channels/drug effects; Calcium Signaling/drug effects; Cell Line; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Embryonic Stem Cells/drug effects; Enzyme Inhibitors/pharmacology; Estrogen Antagonists/pharmacology; Homeodomain Proteins/metabolism; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors/metabolism; Mice; Microscopy, Confocal; NFATC Transcription Factors/genetics; Nanog Homeobox Protein; Pluripotent Stem Cells/drug effects; Recombinant Fusion Proteins/metabolism; SOXB1 Transcription Factors/metabolism; Time Factors; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium Channels / Calcium Signaling / Pluripotent Stem Cells / Cell Proliferation / Estradiol / NFATC Transcription Factors / Embryonic Stem Cells Limits: Animals Language: En Journal: J Cell Physiol Year: 2012 Type: Article Affiliation country: China

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