Serum levels of neuron-specific ubiquitin carboxyl-terminal esterase-L1 predict brain injury in a canine model of hypothermic circulatory arrest.

Arnaoutakis, George J; George, Timothy J; Wang, Kevin K; Wilson, Mary Ann; Allen, Jeremiah G; Robinson, Chase W; Haggerty, Kara A; Weiss, Eric S; Blue, Mary E; Talbot, Charles C; Troncoso, Juan C; Johnston, Michael V; Baumgartner, William A

Arnaoutakis, George J; George, Timothy J; Wang, Kevin K; Wilson, Mary Ann; Allen, Jeremiah G; Robinson, Chase W; Haggerty, Kara A; Weiss, Eric S; Blue, Mary E; Talbot, Charles C; Troncoso, Juan C; Johnston, Michael V; Baumgartner, William A.

Affiliation

Arnaoutakis GJ; Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

J Thorac Cardiovasc Surg ; 142(4): 902-910.e1, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21924148

Subject(s)

Brain Injuries/enzymology; Cardiopulmonary Bypass/adverse effects; Circulatory Arrest, Deep Hypothermia Induced/adverse effects; Neurons/enzymology; Ubiquitin Thiolesterase/blood; Animals; Biomarkers/blood; Biomarkers/cerebrospinal fluid; Brain Injuries/etiology; Brain Injuries/genetics; Brain Injuries/pathology; Brain Injuries/physiopathology; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Immunohistochemistry; Male; Neurologic Examination; Neurons/pathology; Time Factors; Ubiquitin Thiolesterase/cerebrospinal fluid; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Cardiopulmonary Bypass / Ubiquitin Thiolesterase / Circulatory Arrest, Deep Hypothermia Induced / Neurons Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: J Thorac Cardiovasc Surg Year: 2011 Type: Article Affiliation country: United States

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