HIV envelope-mediated, CCR5/&#945;4ß7-dependent killing of CD4-negative Î³Î´ T cells which are lost during progression to AIDS.

Li, Haishan; Pauza, C David

HIV envelope-mediated, CCR5/α4ß7-dependent killing of CD4-negative Î³Î´ T cells which are lost during progression to AIDS.

Li, Haishan; Pauza, C David.

Affiliation

Li H; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Blood ; 118(22): 5824-31, 2011 Nov 24.

Article in En | MEDLINE | ID: mdl-21926353

Subject(s)

Acquired Immunodeficiency Syndrome/immunology; Apoptosis/drug effects; HIV Infections/immunology; Integrins/physiology; Receptors, CCR5/physiology; T-Lymphocytes/drug effects; Viral Envelope Proteins/pharmacology; Acquired Immunodeficiency Syndrome/metabolism; Apoptosis/physiology; CD4 Antigens/metabolism; Cells, Cultured; Disease Progression; HIV/genetics; HIV/physiology; HIV/ultrastructure; HIV Envelope Protein gp120/pharmacology; HIV Envelope Protein gp120/physiology; HIV Infections/pathology; HeLa Cells; Humans; Integrins/metabolism; Receptors, Antigen, T-Cell, gamma-delta/metabolism; Receptors, CCR5/metabolism; T-Lymphocytes/metabolism; T-Lymphocytes/physiology; Viral Envelope Proteins/genetics; Viral Envelope Proteins/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / HIV Infections / Integrins / Viral Envelope Proteins / Acquired Immunodeficiency Syndrome / Apoptosis / Receptors, CCR5 Limits: Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: United States

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