Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis.

Bollée, Guillaume; Flamant, Martin; Schordan, Sandra; Fligny, Cécile; Rumpel, Elisabeth; Milon, Marine; Schordan, Eric; Sabaa, Nathalie; Vandermeersch, Sophie; Galaup, Ariane; Rodenas, Anita; Casal, Ibrahim; Sunnarborg, Susan W; Salant, David J; Kopp, Jeffrey B; Threadgill, David W; Quaggin, Susan E; Dussaule, Jean-Claude; Germain, Stéphane; Mesnard, Laurent; Endlich, Karlhans; Boucheix, Claude; Belenfant, Xavier; Callard, Patrice; Endlich, Nicole; Tharaux, Pierre-Louis

Bollée, Guillaume; Flamant, Martin; Schordan, Sandra; Fligny, Cécile; Rumpel, Elisabeth; Milon, Marine; Schordan, Eric; Sabaa, Nathalie; Vandermeersch, Sophie; Galaup, Ariane; Rodenas, Anita; Casal, Ibrahim; Sunnarborg, Susan W; Salant, David J; Kopp, Jeffrey B; Threadgill, David W; Quaggin, Susan E; Dussaule, Jean-Claude; Germain, Stéphane; Mesnard, Laurent; Endlich, Karlhans; Boucheix, Claude; Belenfant, Xavier; Callard, Patrice; Endlich, Nicole; Tharaux, Pierre-Louis.

Affiliation

Bollée G; Unité Mixte de Recherche (UMR) 970, Paris Cardiovascular Research Centre, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.

Nat Med ; 17(10): 1242-50, 2011 Sep 25.

Article in En | MEDLINE | ID: mdl-21946538

Subject(s)

ErbB Receptors/metabolism; Glomerulonephritis/metabolism; Intercellular Signaling Peptides and Proteins/metabolism; Kidney Glomerulus/injuries; Kidney Glomerulus/physiopathology; Renal Insufficiency/etiology; Analysis of Variance; Animals; Blotting, Western; Bone Marrow Transplantation; Enzyme-Linked Immunosorbent Assay; ErbB Receptors/genetics; Flow Cytometry; Glomerulonephritis/complications; Glomerulonephritis/pathology; Heparin-binding EGF-like Growth Factor; Humans; In Situ Hybridization; Intercellular Signaling Peptides and Proteins/genetics; Kidney Glomerulus/cytology; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Phosphorylation; Podocytes/metabolism; Quinazolines; Real-Time Polymerase Chain Reaction; Statistics, Nonparametric; Tyrphostins

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intercellular Signaling Peptides and Proteins / Renal Insufficiency / ErbB Receptors / Glomerulonephritis / Kidney Glomerulus Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2011 Type: Article Affiliation country: France

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