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RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies.
Harfouche, Carole; Filippini, Sara; Gianfaldoni, Claudia; Ruggiero, Paolo; Moschioni, Monica; Maccari, Silvia; Pancotto, Laura; Arcidiacono, Letizia; Galletti, Bruno; Censini, Stefano; Mori, Elena; Giuliani, Marzia; Facciotti, Claudia; Cartocci, Elena; Savino, Silvana; Doro, Francesco; Pallaoro, Michele; Nocadello, Salvatore; Mancuso, Giuseppe; Haston, Mitch; Goldblatt, David; Barocchi, Michèle A; Pizza, Mariagrazia; Rappuoli, Rino; Masignani, Vega.
Affiliation
  • Harfouche C; Research Center, Novartis Vaccines and Diagnostics s.r.l., Siena, Italy.
Infect Immun ; 80(1): 451-60, 2012 Jan.
Article in En | MEDLINE | ID: mdl-22083702
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptococcus pneumoniae / Blood Bactericidal Activity / Recombinant Fusion Proteins / Opsonin Proteins / Fimbriae, Bacterial / Pneumococcal Vaccines / Fimbriae Proteins Limits: Animals Language: En Journal: Infect Immun Year: 2012 Type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptococcus pneumoniae / Blood Bactericidal Activity / Recombinant Fusion Proteins / Opsonin Proteins / Fimbriae, Bacterial / Pneumococcal Vaccines / Fimbriae Proteins Limits: Animals Language: En Journal: Infect Immun Year: 2012 Type: Article Affiliation country: Italy