Pharmacological and patient-specific response determinants in patients with hospital-acquired pneumonia treated with tigecycline.

Bhavnani, Sujata M; Rubino, Christopher M; Hammel, Jeffrey P; Forrest, Alan; Dartois, Nathalie; Cooper, C Angel; Korth-Bradley, Joan; Ambrose, Paul G

Bhavnani, Sujata M; Rubino, Christopher M; Hammel, Jeffrey P; Forrest, Alan; Dartois, Nathalie; Cooper, C Angel; Korth-Bradley, Joan; Ambrose, Paul G.

Affiliation

Bhavnani SM; Institute for Clinical Pharmacodynamics, Latham, New York, USA. SBhavnani@ICPD.com

Antimicrob Agents Chemother ; 56(2): 1065-72, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22143524

Subject(s)

Anti-Bacterial Agents/pharmacokinetics; Anti-Bacterial Agents/therapeutic use; Cross Infection/drug therapy; Minocycline/analogs & derivatives; Pneumonia, Bacterial/drug therapy; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents/administration & dosage; Anti-Bacterial Agents/pharmacology; Area Under Curve; Cross Infection/microbiology; Double-Blind Method; Female; Gram-Negative Bacteria/drug effects; Gram-Negative Bacteria/isolation & purification; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline/administration & dosage; Minocycline/pharmacokinetics; Minocycline/pharmacology; Minocycline/therapeutic use; Pneumonia, Bacterial/microbiology; Pneumonia, Ventilator-Associated/drug therapy; Pneumonia, Ventilator-Associated/microbiology; Staphylococcus aureus/drug effects; Staphylococcus aureus/isolation & purification; Tigecycline; Treatment Outcome; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cross Infection / Pneumonia, Bacterial / Minocycline / Anti-Bacterial Agents Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Antimicrob Agents Chemother Year: 2012 Type: Article Affiliation country: United States

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