Management of encapsulating peritoneal sclerosis: a guideline on optimal and uniform treatment.
Neth J Med
; 69(11): 500-7, 2011.
Article
in En
| MEDLINE
| ID: mdl-22173363
ABSTRACT
Encapsulating peritoneal sclerosis (EPS) represents a rare complication of long-term peritoneal dialysis (PD). It is characterised by diffuse peritoneal membrane fibrosis, progressive intestinal encapsulation and the clinical spectrum of intestinal obstruction. The pathogenesis is as yet not well understood but includes inflammation, angiogenesis and fibrosis. The current diagnosis of EPS lacks specificity and relies on clinical, radiographic or macroscopic evaluation. There is no general agreement on managing EPS although accumulating clinical data suggest drug treatment (steroids, tamoxifen), surgery (enterolysis) or a combination of both. Here, we provide a short overview on the current knowledge of EPS, with a focus on treatment. Moreover, we present a diagnostic and a therapeutic algorithm for EPS based on the best available published data and our combined experience.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Peritoneal Dialysis
/
Peritoneal Fibrosis
Type of study:
Diagnostic_studies
/
Guideline
Limits:
Humans
Language:
En
Journal:
Neth J Med
Year:
2011
Type:
Article
Affiliation country:
Netherlands