Galantamine-based hybrid molecules with acetylcholinesterase, butyrylcholinesterase and Î³-secretase inhibition activities.

Vezenkov, L; Sevalle, J; Danalev, D; Ivanov, T; Bakalova, A; Georgieva, M; Checler, F

Vezenkov, L; Sevalle, J; Danalev, D; Ivanov, T; Bakalova, A; Georgieva, M; Checler, F.

Affiliation

Vezenkov L; Department of Organic Chemistry, University of Chemical Technology and Metallurgy, 8 Kl. Ohridski blvd., 1756 Sofia, Bulgaria. lvezenkov@yahoo.com

Curr Alzheimer Res ; 9(5): 600-5, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22211487

Subject(s)

Acetylcholinesterase/drug effects; Amyloid Precursor Protein Secretases/drug effects; Butyrylcholinesterase/drug effects; Enzyme Inhibitors/pharmacology; Galantamine/analogs & derivatives; Oligopeptides/pharmacology; Drug Design; Galantamine/pharmacology; HEK293 Cells/drug effects; HEK293 Cells/enzymology; Humans; Neuroprotective Agents/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Acetylcholinesterase / Butyrylcholinesterase / Enzyme Inhibitors / Amyloid Precursor Protein Secretases / Galantamine Limits: Humans Language: En Journal: Curr Alzheimer Res Journal subject: NEUROLOGIA Year: 2012 Type: Article Affiliation country: Bulgaria

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