Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells.

Chuang, J-Y; Wang, S-A; Yang, W-B; Yang, H-C; Hung, C-Y; Su, T-P; Chang, W-C; Hung, J-J

Chuang, J-Y; Wang, S-A; Yang, W-B; Yang, H-C; Hung, C-Y; Su, T-P; Chang, W-C; Hung, J-J.

Affiliation

Chuang JY; Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, Tainan, Taiwan.

Oncogene ; 31(47): 4946-59, 2012 Nov 22.

Article in En | MEDLINE | ID: mdl-22266860

Subject(s)

CDC2 Protein Kinase/metabolism; Cyclin B1/metabolism; Gene Expression Regulation, Neoplastic; Mitosis; Sp1 Transcription Factor/metabolism; Actins/metabolism; Adenocarcinoma/chemically induced; Adenocarcinoma/metabolism; Amino Acid Motifs; Animals; Chromatin Assembly and Disassembly; Enzyme Activation; Female; HeLa Cells; Humans; Interphase; Mammary Neoplasms, Animal/chemically induced; Mammary Neoplasms, Animal/metabolism; Methylnitrosourea; Myosins/metabolism; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Phosphatase 2/metabolism; Protein Processing, Post-Translational; Rats; Threonine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / CDC2 Protein Kinase / Sp1 Transcription Factor / Cyclin B1 / Mitosis Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2012 Type: Article Affiliation country: Taiwan

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