Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells.

Lange, Yvonne; Ye, Jin; Steck, Theodore L

Lange, Yvonne; Ye, Jin; Steck, Theodore L.

Affiliation

Lange Y; Department of Pathology, Rush University Medical Center, Chicago, Illinois, United States of America. ylange@rush.edu

PLoS One ; 7(1): e30051, 2012.

Article in En | MEDLINE | ID: mdl-22276143

Subject(s)

Cholesterol/metabolism; Endosomes/metabolism; Lysosomes/metabolism; Niemann-Pick Diseases/metabolism; Androstenes/pharmacology; Biological Transport/drug effects; Cells, Cultured; Chlorpromazine/pharmacology; Cholesterol Oxidase/metabolism; Endosomes/drug effects; Fibroblasts/drug effects; Fibroblasts/metabolism; Humans; Lysosomes/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Niemann-Pick Diseases / Cholesterol / Lysosomes Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Type: Article Affiliation country: United States

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