Syntheses of structurally-simplified and fluorescently-labeled neovibsanin derivatives and analysis of their neurite outgrowth activity in PC12 cells.

Imagawa, Hiroshi; Saijo, Hayato; Yamaguchi, Hitomi; Maekawa, Ken; Kurisaki, Takahiro; Yamamoto, Hirofumi; Nishizawa, Mugio; Oda, Masataka; Kabura, Michiko; Nagahama, Masahiro; Sakurai, Jun; Kubo, Miwa; Nakai, Megumi; Makino, Kosho; Ogata, Mitsuko; Takahashi, Hironobu; Fukuyama, Yoshiyasu

Imagawa, Hiroshi; Saijo, Hayato; Yamaguchi, Hitomi; Maekawa, Ken; Kurisaki, Takahiro; Yamamoto, Hirofumi; Nishizawa, Mugio; Oda, Masataka; Kabura, Michiko; Nagahama, Masahiro; Sakurai, Jun; Kubo, Miwa; Nakai, Megumi; Makino, Kosho; Ogata, Mitsuko; Takahashi, Hironobu; Fukuyama, Yoshiyasu.

Affiliation

Imagawa H; Chemistry of Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cyo, Tokushima, Japan. imagawa@ph.bunri-u.ac.jp

Bioorg Med Chem Lett ; 22(5): 2089-93, 2012 Mar 01.

Article in En | MEDLINE | ID: mdl-22305582

Subject(s)

Diterpenes/chemistry; Diterpenes/pharmacology; Neurites/drug effects; Neurogenesis/drug effects; Neurons/cytology; Viburnum/chemistry; Animals; Diterpenes/analysis; Diterpenes/chemical synthesis; Fluorescent Dyes/chemistry; Models, Molecular; Neurites/ultrastructure; Neurons/drug effects; Neurons/ultrastructure; PC12 Cells; Rats

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurites / Viburnum / Diterpenes / Neurogenesis / Neurons Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Type: Article Affiliation country: Japan

Fulltext

XML

PubMed Links

Search on Google