SIRT1 overexpression decreases cisplatin-induced acetylation of NF-&#954;B p65 subunit and cytotoxicity in renal proximal tubule cells.

Jung, Yu Jin; Lee, Jung Eun; Lee, Ae Sin; Kang, Kyung Pyo; Lee, Sik; Park, Sung Kwang; Lee, Sang Yong; Han, Myung Kwan; Kim, Duk Hoon; Kim, Won

SIRT1 overexpression decreases cisplatin-induced acetylation of NF-κB p65 subunit and cytotoxicity in renal proximal tubule cells.

Jung, Yu Jin; Lee, Jung Eun; Lee, Ae Sin; Kang, Kyung Pyo; Lee, Sik; Park, Sung Kwang; Lee, Sang Yong; Han, Myung Kwan; Kim, Duk Hoon; Kim, Won.

Affiliation

Jung YJ; Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, South Korea.

Biochem Biophys Res Commun ; 419(2): 206-10, 2012 Mar 09.

Article in En | MEDLINE | ID: mdl-22330808

Subject(s)

Antineoplastic Agents/adverse effects; Cisplatin/adverse effects; Kidney Tubules, Proximal/drug effects; Sirtuin 1/biosynthesis; Transcription Factor RelA/metabolism; Acetylation; Antioxidants/pharmacology; Carbazoles/pharmacology; Cell Line; Drug Resistance, Neoplasm; Humans; Kidney Tubules, Proximal/metabolism; Protein Biosynthesis/drug effects; Resveratrol; Sirtuin 1/antagonists & inhibitors; Stilbenes/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cisplatin / Transcription Factor RelA / Sirtuin 1 / Kidney Tubules, Proximal / Antineoplastic Agents Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2012 Type: Article Affiliation country: South Korea

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