Substance P causes seizures in neurocysticercosis.

Robinson, Prema; Garza, Armandina; Weinstock, Joel; Serpa, Jose A; Goodman, Jerry Clay; Eckols, Kristian T; Firozgary, Bahrom; Tweardy, David J

Robinson, Prema; Garza, Armandina; Weinstock, Joel; Serpa, Jose A; Goodman, Jerry Clay; Eckols, Kristian T; Firozgary, Bahrom; Tweardy, David J.

Affiliation

Robinson P; Department of Medicine, Baylor College of Medicine, Houston, Texas, United States of America. premar@bcm.edu

PLoS Pathog ; 8(2): e1002489, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22346746

Subject(s)

Brain Diseases/complications; Granuloma/parasitology; Neurocysticercosis/complications; Seizures/etiology; Substance P/metabolism; Animals; Brain/pathology; Brain Diseases/parasitology; Brain Diseases/pathology; Disease Models, Animal; Female; Gene Deletion; Granuloma/metabolism; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neurocysticercosis/parasitology; Neurocysticercosis/pathology; Neurokinin-1 Receptor Antagonists/therapeutic use; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1/genetics; Receptors, Neurokinin-1/physiology; Seizures/drug therapy; Seizures/parasitology; Seizures/prevention & control; Substance P/analysis; Substance P/antagonists & inhibitors; Substance P/isolation & purification; Taenia/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Seizures / Brain Diseases / Substance P / Neurocysticercosis / Granuloma Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: PLoS Pathog Year: 2012 Type: Article Affiliation country: United States

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