Preventing thiol-yne addition improves the specificity of strain-promoted azide-alkyne cycloaddition.

van Geel, Remon; Pruijn, Ger J M; van Delft, Floris L; Boelens, Wilbert C

van Geel, Remon; Pruijn, Ger J M; van Delft, Floris L; Boelens, Wilbert C.

Affiliation

van Geel R; Biomolecular Chemistry, Nijmegen Center for Molecular Life Sciences, Institute for Molecules and Materials and Netherlands Proteomics Centre, Radboud University Nijmegen, The Netherlands.

Bioconjug Chem ; 23(3): 392-8, 2012 Mar 21.

Article in En | MEDLINE | ID: mdl-22372991

Subject(s)

Alkynes/chemistry; Azides/chemistry; Proteins/chemistry; Sulfhydryl Compounds/chemistry; Blotting, Western; Chromatography, Liquid; Cyclization; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfhydryl Compounds / Azides / Proteins / Alkynes Limits: Humans Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2012 Type: Article Affiliation country: Netherlands

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