Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line.

Wu, Jia Qian; Seay, Montrell; Schulz, Vincent P; Hariharan, Manoj; Tuck, David; Lian, Jin; Du, Jiang; Shi, Minyi; Ye, Zhijia; Gerstein, Mark; Snyder, Michael P; Weissman, Sherman

Wu, Jia Qian; Seay, Montrell; Schulz, Vincent P; Hariharan, Manoj; Tuck, David; Lian, Jin; Du, Jiang; Shi, Minyi; Ye, Zhijia; Gerstein, Mark; Snyder, Michael P; Weissman, Sherman.

Affiliation

Wu JQ; Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America. Jiaqian2009.wu@gmail.com

PLoS Genet ; 8(3): e1002565, 2012.

Article in En | MEDLINE | ID: mdl-22412390

Subject(s)

Cell Differentiation; Cell Proliferation; Core Binding Factor Alpha 2 Subunit; Hematopoietic Stem Cells/metabolism; T Cell Transcription Factor 1/genetics; T Cell Transcription Factor 1/metabolism; Animals; Antigens, CD34/metabolism; Cell Line; Core Binding Factor Alpha 2 Subunit/genetics; Core Binding Factor Alpha 2 Subunit/metabolism; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Hematopoietic Stem Cells/cytology; Hepatocyte Nuclear Factor 1-alpha; Humans; Mice; Promoter Regions, Genetic; Protein Binding; RNA, Small Interfering; Sequence Analysis, RNA; T Cell Transcription Factor 1/antagonists & inhibitors; Transcription Factors/classification; Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Cell Differentiation / Cell Proliferation / T Cell Transcription Factor 1 / Core Binding Factor Alpha 2 Subunit Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2012 Type: Article Affiliation country: United States

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