Glycosaminoglycan backbone is not required for the modulation of hemostasis: effect of different heparin derivatives and non-glycosaminoglycan analogs.

Bouças, Rodrigo I; Jarrouge-Bouças, Thais R; Lima, Marcelo A; Trindade, Edvaldo S; Moraes, Fabio A; Cavalheiro, Renan P; Tersariol, Ivarne L S; Hoppenstead, Debra; Fareed, Jawed; Nader, Helena B

Bouças, Rodrigo I; Jarrouge-Bouças, Thais R; Lima, Marcelo A; Trindade, Edvaldo S; Moraes, Fabio A; Cavalheiro, Renan P; Tersariol, Ivarne L S; Hoppenstead, Debra; Fareed, Jawed; Nader, Helena B.

Affiliation

Bouças RI; Disciplina de Biologia Molecular, Departamento de Bioquímica, Universidade Federal de São Paulo, SP, Brazil.

Matrix Biol ; 31(5): 308-16, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22504459

Subject(s)

Extracellular Matrix/drug effects; Hemostasis; Heparin/analogs & derivatives; Heparin/pharmacology; Animals; Anticoagulants/pharmacology; Binding Sites; Dose-Response Relationship, Drug; Endothelial Cells/chemistry; Endothelial Cells/drug effects; Extracellular Matrix/chemistry; Fibrinolytic Agents/pharmacology; Heparin Lyase/chemistry; Molecular Weight; Myocytes, Smooth Muscle/chemistry; Myocytes, Smooth Muscle/drug effects; Oligosaccharides/pharmacology; Protein Binding; Proteolysis; Rabbits; Rats; Substrate Specificity

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin / Extracellular Matrix / Hemostasis Limits: Animals Language: En Journal: Matrix Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2012 Type: Article Affiliation country: Brazil

Fulltext

XML

PubMed Links

Search on Google