2,5-dihydroxyacetophenone isolated from Rehmanniae Radix Preparata inhibits inflammatory responses in lipopolysaccharide-stimulated RAW264.7 macrophages.

Han, Yunkyung; Jung, Hyo Won; Lee, Joo Young; Kim, Ju Sun; Kang, Sam Sik; Kim, Yeong Shik; Park, Yong-Ki

Han, Yunkyung; Jung, Hyo Won; Lee, Joo Young; Kim, Ju Sun; Kang, Sam Sik; Kim, Yeong Shik; Park, Yong-Ki.

Affiliation

Han Y; Oriental Medicine R&D Center, Dongguk University, Gyeongju, Korea.

J Med Food ; 15(6): 505-10, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22510152

Subject(s)

Acetophenones/therapeutic use; Anti-Inflammatory Agents/therapeutic use; Inflammation Mediators/metabolism; Inflammation/drug therapy; Macrophages/drug effects; Phytotherapy; Rehmannia/chemistry; Acetophenones/isolation & purification; Acetophenones/pharmacology; Animals; Anti-Inflammatory Agents/isolation & purification; Anti-Inflammatory Agents/pharmacology; Cytokines/biosynthesis; Cytokines/genetics; Cytokines/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Inflammation/chemically induced; Inflammation/metabolism; Lipopolysaccharides; Macrophages/metabolism; Mice; NF-kappa B/metabolism; Phosphorylation; Plant Extracts/chemistry; Plant Extracts/pharmacology; Plant Extracts/therapeutic use; Plant Roots; RNA, Messenger/metabolism; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetophenones / Inflammation Mediators / Rehmannia / Inflammation / Macrophages / Phytotherapy / Anti-Inflammatory Agents Limits: Animals Language: En Journal: J Med Food Journal subject: CIENCIAS DA NUTRICAO / MEDICINA Year: 2012 Type: Article

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