Protein kinase C&#945; and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog.

Guo, Daorong; Standley, Clive; Bellve, Karl; Fogarty, Kevin; Bao, Zheng-Zheng

Protein kinase Cα and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog.

Guo, Daorong; Standley, Clive; Bellve, Karl; Fogarty, Kevin; Bao, Zheng-Zheng.

Affiliation

Guo D; Department of Medicine and Cell Biology, Program in Neuroscience, University of Massachusetts Medical School, Worcester, MA 01605, USA. daorong.guo@umassmed.edu

Mol Cell Neurosci ; 50(1): 82-92, 2012 May.

Article in En | MEDLINE | ID: mdl-22521536

Subject(s)

Axons/enzymology; Hedgehog Proteins/metabolism; Protein Kinase C-alpha/metabolism; Protein Serine-Threonine Kinases/metabolism; Acetophenones/pharmacology; Animals; Axons/physiology; Benzopyrans/pharmacology; Calcium/metabolism; Cells, Cultured; Chick Embryo; Enzyme Inhibitors/pharmacology; Growth Cones/enzymology; Mutation; Phosphorylation; Protein Kinase C-alpha/antagonists & inhibitors; Protein Kinase C-alpha/genetics; Protein Serine-Threonine Kinases/genetics; Retinal Ganglion Cells/cytology; Retinal Ganglion Cells/enzymology; Threonine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Protein Serine-Threonine Kinases / Protein Kinase C-alpha / Hedgehog Proteins Type of study: Guideline Limits: Animals Language: En Journal: Mol Cell Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2012 Type: Article Affiliation country: United States

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