Colon/immunology; Dinoprostone/immunology; Epithelial Cells/immunology; Gene Expression Regulation/immunology; Interleukin-8/immunology; Intestinal Mucosa/immunology; Caco-2 Cells; Colon/cytology; Colon/metabolism; Cyclic AMP Response Element Modulator/genetics; Cyclic AMP Response Element Modulator/immunology; Cyclic AMP Response Element Modulator/metabolism; Cyclic AMP Response Element-Binding Protein/genetics; Cyclic AMP Response Element-Binding Protein/immunology; Cyclic AMP Response Element-Binding Protein/metabolism; Cyclic AMP-Dependent Protein Kinases/genetics; Cyclic AMP-Dependent Protein Kinases/immunology; Cyclic AMP-Dependent Protein Kinases/metabolism; Dinoprostone/genetics; Dinoprostone/metabolism; Epithelial Cells/cytology; Epithelial Cells/metabolism; Gene Expression Regulation/genetics; Humans; Interleukin-8/biosynthesis; Interleukin-8/genetics; Intestinal Mucosa/cytology; Intestinal Mucosa/metabolism; Multiprotein Complexes/genetics; Multiprotein Complexes/metabolism; Phosphatidylinositol 3-Kinases/genetics; Phosphatidylinositol 3-Kinases/immunology; Phosphatidylinositol 3-Kinases/metabolism; Receptors, Prostaglandin E, EP2 Subtype/genetics; Receptors, Prostaglandin E, EP2 Subtype/immunology; Receptors, Prostaglandin E, EP2 Subtype/metabolism; Receptors, Prostaglandin E, EP4 Subtype/genetics; Receptors, Prostaglandin E, EP4 Subtype/immunology; Receptors, Prostaglandin E, EP4 Subtype/metabolism; Response Elements/genetics; Response Elements/immunology; Signal Transduction/genetics; Signal Transduction/immunology