Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model.

Verret, Laure; Mann, Edward O; Hang, Giao B; Barth, Albert M I; Cobos, Inma; Ho, Kaitlyn; Devidze, Nino; Masliah, Eliezer; Kreitzer, Anatol C; Mody, Istvan; Mucke, Lennart; Palop, Jorge J

Verret, Laure; Mann, Edward O; Hang, Giao B; Barth, Albert M I; Cobos, Inma; Ho, Kaitlyn; Devidze, Nino; Masliah, Eliezer; Kreitzer, Anatol C; Mody, Istvan; Mucke, Lennart; Palop, Jorge J.

Affiliation

Verret L; Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.

Cell ; 149(3): 708-21, 2012 Apr 27.

Article in En | MEDLINE | ID: mdl-22541439

Subject(s)

Alzheimer Disease/physiopathology; Amyloid beta-Protein Precursor/metabolism; Animals; Disease Models, Animal; Hippocampus/metabolism; Humans; In Vitro Techniques; Interneurons/metabolism; Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins/metabolism; Neurons/metabolism; Sodium Channels/metabolism; Synapses

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Limits: Animals / Humans Language: En Journal: Cell Year: 2012 Type: Article Affiliation country: United States

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