Integrin &#945;5ß1 activates the NLRP3 inflammasome by direct interaction with a bacterial surface protein.

Jun, Hye-Kyoung; Lee, Sung-Hoon; Lee, Hae-Ri; Choi, Bong-Kyu

Integrin α5ß1 activates the NLRP3 inflammasome by direct interaction with a bacterial surface protein.

Jun, Hye-Kyoung; Lee, Sung-Hoon; Lee, Hae-Ri; Choi, Bong-Kyu.

Affiliation

Jun HK; Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Immunity ; 36(5): 755-68, 2012 May 25.

Article in En | MEDLINE | ID: mdl-22608495

Subject(s)

Bacterial Outer Membrane Proteins/metabolism; Carrier Proteins/metabolism; Inflammasomes/metabolism; Integrin alpha5beta1/metabolism; Adenosine Triphosphate/metabolism; Caspase 1/metabolism; Cell Death; Cell Line; Humans; Inflammation/metabolism; Interleukin-1beta/metabolism; Macrophages/metabolism; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium/metabolism; Receptors, Purinergic P2/metabolism; Treponema denticola/metabolism; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Outer Membrane Proteins / Carrier Proteins / Integrin alpha5beta1 / Inflammasomes Type of study: Prognostic_studies Limits: Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2012 Type: Article

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