KRAS mutations in primary tumours and post-FOLFOX metastatic lesions in cases of colorectal cancer.

Kawamoto, Y; Tsuchihara, K; Yoshino, T; Ogasawara, N; Kojima, M; Takahashi, M; Ochiai, A; Bando, H; Fuse, N; Tahara, M; Doi, T; Esumi, H; Komatsu, Y; Ohtsu, A

Kawamoto, Y; Tsuchihara, K; Yoshino, T; Ogasawara, N; Kojima, M; Takahashi, M; Ochiai, A; Bando, H; Fuse, N; Tahara, M; Doi, T; Esumi, H; Komatsu, Y; Ohtsu, A.

Affiliation

Kawamoto Y; Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan.

Br J Cancer ; 107(2): 340-4, 2012 Jul 10.

Article in En | MEDLINE | ID: mdl-22617127

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Colorectal Neoplasms/drug therapy; Colorectal Neoplasms/genetics; Mutation; Proto-Oncogene Proteins/genetics; ras Proteins/genetics; Adult; Aged; Biomarkers, Tumor/genetics; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms/metabolism; Colorectal Neoplasms/pathology; Disease-Free Survival; ErbB Receptors/genetics; ErbB Receptors/metabolism; Female; Fluorouracil/therapeutic use; Genes, ras; Humans; Leucovorin/therapeutic use; Male; Middle Aged; Organoplatinum Compounds/therapeutic use; Phosphatidylinositol 3-Kinases/genetics; Proto-Oncogene Proteins B-raf/genetics; Proto-Oncogene Proteins p21(ras)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Proto-Oncogene Proteins / Ras Proteins / Mutation Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2012 Type: Article Affiliation country: Japan

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