Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin.

Ljunggren, Ö; Bolinder, J; Johansson, L; Wilding, J; Langkilde, A M; Sjöström, C D; Sugg, J; Parikh, S

Ljunggren, Ö; Bolinder, J; Johansson, L; Wilding, J; Langkilde, A M; Sjöström, C D; Sugg, J; Parikh, S.

Affiliation

Ljunggren Ö; Osteoporosis Research Unit, Department of Medical Sciences, Uppsala University, Uppsala, Sweden. osten.ljunggren@medsci.uu.se

Diabetes Obes Metab ; 14(11): 990-9, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22651373

Subject(s)

Bone Density/drug effects; Diabetes Mellitus, Type 2/drug therapy; Glucosides/pharmacology; Hypoglycemic Agents/pharmacology; Metformin/pharmacology; Osteogenesis/drug effects; Osteoporosis/etiology; Absorptiometry, Photon; Adult; Aged; Benzhydryl Compounds; Blood Glucose/metabolism; Body Mass Index; Diabetes Mellitus, Type 2/complications; Diabetes Mellitus, Type 2/physiopathology; Double-Blind Method; Female; Glucosides/administration & dosage; Glucosides/pharmacokinetics; Humans; Hypoglycemic Agents/administration & dosage; Male; Metformin/administration & dosage; Middle Aged; Osteoporosis/chemically induced; Osteoporosis/physiopathology; Time Factors; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteogenesis / Osteoporosis / Bone Density / Diabetes Mellitus, Type 2 / Glucosides / Hypoglycemic Agents / Metformin Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Diabetes Obes Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2012 Type: Article Affiliation country: Sweden

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