Sequence of a sea urchin hsp70 gene and its 5' flanking region.
Gene
; 96(2): 295-300, 1990 Dec 15.
Article
in En
| MEDLINE
| ID: mdl-2269441
ABSTRACT
We report the nucleotide sequence of a 4470-bp fragment derived from a sea urchin genomic clone containing part of a heat-shock protein 70 (Hsp70)-encoding gene. This fragment, named hsp70 gene II, contains 1271 bp of the flanking region and 3299 bp of structural gene sequence interrupted by five introns and encoding the N-terminal 371 amino acids (aa) of the protein. The 5' flanking region contains a putative TATA element, two CCAAT boxes, four heat-shock consensus sequence elements (hse) and one consensus sequence for binding of Sp1. Remarkable homologies were observed for deduced aa sequence and intron-exon organization between hsp70 gene II and rat hsc73 gene.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sea Urchins
/
Heat-Shock Proteins
Limits:
Animals
Language:
En
Journal:
Gene
Year:
1990
Type:
Article
Affiliation country:
Italy