Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade.

Wei, Tong-You W; Juan, Chi-Chang; Hisa, Jiun-Yi; Su, Li-Jen; Lee, Yuan-Chii G; Chou, Hsiang-Yun; Chen, Jo-Mei M; Wu, Yu-Chung; Chiu, Shao-Chih; Hsu, Chung-Ping; Liu, Kuo-Lin; Yu, Chang-Tze R

Wei, Tong-You W; Juan, Chi-Chang; Hisa, Jiun-Yi; Su, Li-Jen; Lee, Yuan-Chii G; Chou, Hsiang-Yun; Chen, Jo-Mei M; Wu, Yu-Chung; Chiu, Shao-Chih; Hsu, Chung-Ping; Liu, Kuo-Lin; Yu, Chang-Tze R.

Affiliation

Wei TY; Graduate Institute of Biomedicine and Biomedical Technology, National Chi Nan University, Puli, Taiwan.

Cancer Sci ; 103(9): 1640-50, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22726390

Subject(s)

Cyclin-Dependent Kinases/metabolism; G1 Phase; Oncogene Proteins/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Protein-Arginine N-Methyltransferases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic/genetics; Cell Transformation, Neoplastic/metabolism; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms/genetics; Lung Neoplasms/metabolism; Mice; Mice, Nude; Oncogene Proteins/genetics; Protein-Arginine N-Methyltransferases/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Arginine N-Methyltransferases / Signal Transduction / G1 Phase / Oncogene Proteins / Cyclin-Dependent Kinases / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt Limits: Animals / Humans Language: En Journal: Cancer Sci Year: 2012 Type: Article Affiliation country: Taiwan

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