Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.

Lim, Justin W E; Mathias, Rommel A; Kapp, Eugene A; Layton, Meredith J; Faux, Maree C; Burgess, Antony W; Ji, Hong; Simpson, Richard J

Lim, Justin W E; Mathias, Rommel A; Kapp, Eugene A; Layton, Meredith J; Faux, Maree C; Burgess, Antony W; Ji, Hong; Simpson, Richard J.

Affiliation

Lim JW; Joint Proteomics Research Laboratory, Ludwig Institute for Cancer Research and The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Electrophoresis ; 33(12): 1873-80, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22740476

Subject(s)

Adenomatous Polyposis Coli Protein/metabolism; Colonic Neoplasms/metabolism; Exosomes/metabolism; Intercellular Signaling Peptides and Proteins/metabolism; Adenomatous Polyposis Coli Protein/genetics; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases/genetics; DNA (Cytosine-5-)-Methyltransferases/metabolism; DNA Methyltransferase 3A; Exosomes/chemistry; Humans; Intercellular Signaling Peptides and Proteins/genetics; Methylation; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteome/analysis; Proteome/genetics; Proteome/metabolism; Proteomics; Up-Regulation; Wnt Signaling Pathway

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colonic Neoplasms / Adenomatous Polyposis Coli Protein / Intercellular Signaling Peptides and Proteins / Exosomes Limits: Humans Language: En Journal: Electrophoresis Year: 2012 Type: Article Affiliation country: Australia

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