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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.
Straussman, Ravid; Morikawa, Teppei; Shee, Kevin; Barzily-Rokni, Michal; Qian, Zhi Rong; Du, Jinyan; Davis, Ashli; Mongare, Margaret M; Gould, Joshua; Frederick, Dennie T; Cooper, Zachary A; Chapman, Paul B; Solit, David B; Ribas, Antoni; Lo, Roger S; Flaherty, Keith T; Ogino, Shuji; Wargo, Jennifer A; Golub, Todd R.
Affiliation
  • Straussman R; The Eli and Edythe L. Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.
Nature ; 487(7408): 500-4, 2012 Jul 26.
Article in En | MEDLINE | ID: mdl-22763439
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatocyte Growth Factor / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Tumor Microenvironment / Melanoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2012 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatocyte Growth Factor / Drug Resistance, Neoplasm / Proto-Oncogene Proteins B-raf / Tumor Microenvironment / Melanoma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2012 Type: Article Affiliation country: United States