In vivo evaluation of the highly soluble oral ß-cyclodextrin-Sertraline supramolecular complexes.

Passos, Joel J; De Sousa, Frederico B; Mundim, Iram M; Bonfim, Ricardo R; Melo, Robson; Viana, Alice F; Stolz, Eveline D; Borsoi, Milene; Rates, Stela M K; Sinisterra, Rubén D

Passos, Joel J; De Sousa, Frederico B; Mundim, Iram M; Bonfim, Ricardo R; Melo, Robson; Viana, Alice F; Stolz, Eveline D; Borsoi, Milene; Rates, Stela M K; Sinisterra, Rubén D.

Affiliation

Passos JJ; Laboratório de Encapsulamento Molecular e Biomateriais (LEMB) - Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG 31270-901, Brazil.

Int J Pharm ; 436(1-2): 478-85, 2012 Oct 15.

Article in En | MEDLINE | ID: mdl-22772486

Subject(s)

Antidepressive Agents/pharmacology; Sertraline/pharmacology; beta-Cyclodextrins/pharmacology; Animals; Antidepressive Agents/blood; Antidepressive Agents/chemistry; Hindlimb Suspension; Male; Mice; Motor Activity/drug effects; Powder Diffraction; Sertraline/blood; Sertraline/chemistry; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction; beta-Cyclodextrins/chemistry

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sertraline / Beta-Cyclodextrins / Antidepressive Agents Limits: Animals Language: En Journal: Int J Pharm Year: 2012 Type: Article Affiliation country: Brazil

Fulltext

XML

PubMed Links

Search on Google