Down regulation of differentiated embryonic chondrocytes 1 (DEC1) is involved in 8-methoxypsoralen-induced apoptosis in HepG2 cells.

Peng, Yan; Liu, Wei; Xiong, Jing; Gui, Hai Yan; Feng, Xue Min; Chen, Rui Ni; Hu, Gang; Yang, Jian

Peng, Yan; Liu, Wei; Xiong, Jing; Gui, Hai Yan; Feng, Xue Min; Chen, Rui Ni; Hu, Gang; Yang, Jian.

Affiliation

Peng Y; Department of Pharmacology, Nanjing Medical University, Nanjing, Jiangsu 210029, China.

Toxicology ; 301(1-3): 58-65, 2012 Nov 15.

Article in En | MEDLINE | ID: mdl-22796345

Subject(s)

Basic Helix-Loop-Helix Transcription Factors/genetics; Carcinoma, Hepatocellular/drug therapy; Down-Regulation/drug effects; Homeodomain Proteins/genetics; Liver Neoplasms/drug therapy; Methoxsalen/pharmacology; Apoptosis/drug effects; Carcinoma, Hepatocellular/pathology; Caspase 3/metabolism; Caspase 8/metabolism; Caspase 9/metabolism; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Inhibitor of Apoptosis Proteins/metabolism; Inhibitory Concentration 50; Liver Neoplasms/pathology; Methoxsalen/administration & dosage; Photosensitizing Agents/administration & dosage; Photosensitizing Agents/pharmacology; Survivin; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Carcinoma, Hepatocellular / Homeodomain Proteins / Basic Helix-Loop-Helix Transcription Factors / Liver Neoplasms / Methoxsalen Limits: Humans Language: En Journal: Toxicology Year: 2012 Type: Article Affiliation country: China

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