Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat.

Lie, Pearl P Y; Mruk, Dolores D; Mok, Ka Wai; Su, Linlin; Lee, Will M; Cheng, C Yan

Lie, Pearl P Y; Mruk, Dolores D; Mok, Ka Wai; Su, Linlin; Lee, Will M; Cheng, C Yan.

Affiliation

Lie PP; The Mary M Wohlford Laboratory for Male Contraceptive Research, Center for Biomedical Research, Population Council, New York, NY 10065, USA.

Proc Natl Acad Sci U S A ; 109(31): 12562-7, 2012 Jul 31.

Article in En | MEDLINE | ID: mdl-22797892

Subject(s)

Blood-Testis Barrier/enzymology; Focal Adhesion Kinase 1/metabolism; Sertoli Cells/metabolism; Tight Junctions/enzymology; Actins/genetics; Actins/metabolism; Amino Acid Substitution; Animals; Blood-Testis Barrier/cytology; Cytoskeleton/genetics; Cytoskeleton/metabolism; Focal Adhesion Kinase 1/genetics; Male; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mutation, Missense; Phosphoproteins/genetics; Phosphoproteins/metabolism; Phosphorylation/genetics; Protein Multimerization/physiology; Rats; Sertoli Cells/cytology; Spermatocytes/cytology; Spermatocytes/enzymology; Spermatogenesis/physiology; Tight Junctions/genetics; Wiskott-Aldrich Syndrome Protein/genetics; Wiskott-Aldrich Syndrome Protein/metabolism; Zonula Occludens-1 Protein

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sertoli Cells / Blood-Testis Barrier / Tight Junctions / Focal Adhesion Kinase 1 Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2012 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google