Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1.

Yuki, Koichi; Bu, Weiming; Xi, Jin; Sen, Mehmet; Shimaoka, Motomu; Eckenhoff, Roderic G

Yuki, Koichi; Bu, Weiming; Xi, Jin; Sen, Mehmet; Shimaoka, Motomu; Eckenhoff, Roderic G.

Affiliation

Yuki K; Department of Anesthesiology, Perioperative and Pain Medicine, Children's Hospital Boston, 300 Longwood Ave., Boston, MA 02115, USA. koichi.yuki@childrens.harvard.edu

FASEB J ; 26(11): 4408-17, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22815384

Subject(s)

Isoflurane/metabolism; Lymphocyte Function-Associated Antigen-1/chemistry; Lymphocyte Function-Associated Antigen-1/metabolism; Amino Acid Sequence; Antibodies, Monoclonal; Binding Sites; HEK293 Cells; Humans; Isoflurane/chemistry; Models, Molecular; Molecular Sequence Data; Mutagenesis; Protein Binding; Protein Conformation; Protein Structure, Tertiary

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Function-Associated Antigen-1 / Isoflurane Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2012 Type: Article Affiliation country: United States

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