Chemical proteomics reveals heat shock protein 60 to be the main cellular target of the marine bioactive sesterterpene suvanine.

Cassiano, Chiara; Monti, Maria Chiara; Festa, Carmen; Zampella, Angela; Riccio, Raffaele; Casapullo, Agostino

Cassiano, Chiara; Monti, Maria Chiara; Festa, Carmen; Zampella, Angela; Riccio, Raffaele; Casapullo, Agostino.

Affiliation

Cassiano C; Dipartimento di Scienze Farmaceutiche e BioMediche, Università degli Studi di Salerno, Via Ponte don Melillo, Fisciano, Salerno, Italy.

Chembiochem ; 13(13): 1953-8, 2012 Sep 03.

Article in En | MEDLINE | ID: mdl-22829539

Subject(s)

Anti-Inflammatory Agents/pharmacology; Chaperonin 60/antagonists & inhibitors; Chaperonin 60/metabolism; Porifera/metabolism; Sesterterpenes/pharmacology; Animals; Anti-Inflammatory Agents/chemistry; Anti-Inflammatory Agents/metabolism; HeLa Cells; Humans; Mass Spectrometry; Porifera/chemistry; Proteomics; Recombinant Proteins/antagonists & inhibitors; Recombinant Proteins/metabolism; Sesterterpenes/chemistry; Sesterterpenes/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Porifera / Chaperonin 60 / Sesterterpenes / Anti-Inflammatory Agents Limits: Animals / Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2012 Type: Article Affiliation country: Italy

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