Circumventing antivector immunity by using adenovirus-infected blood cells for repeated application of adenovirus-vectored vaccines: proof of concept in rhesus macaques.

Sun, Caijun; Feng, Liqiang; Zhang, Yinfeng; Xiao, Lijun; Pan, Weiqi; Li, Chufang; Zhang, Linqi; Chen, Ling

Sun, Caijun; Feng, Liqiang; Zhang, Yinfeng; Xiao, Lijun; Pan, Weiqi; Li, Chufang; Zhang, Linqi; Chen, Ling.

Affiliation

Sun C; State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.

J Virol ; 86(20): 11031-42, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22855499

Subject(s)

Adenoviridae/immunology; Antibodies, Viral/immunology; SAIDS Vaccines/genetics; SAIDS Vaccines/immunology; Adenovirus Vaccines; Animals; Antibodies, Neutralizing/immunology; Antibodies, Viral/blood; Gene Products, env/immunology; Gene Products, gag/immunology; Gene Products, pol/immunology; Genetic Vectors; Humans; Leukocytes, Mononuclear/virology; Lipopolysaccharide Receptors/biosynthesis; Macaca mulatta; Simian Immunodeficiency Virus/genetics; Simian Immunodeficiency Virus/immunology; Viral Vaccines/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenoviridae / SAIDS Vaccines / Antibodies, Viral Limits: Animals / Humans Language: En Journal: J Virol Year: 2012 Type: Article Affiliation country: China

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