Determination of severity of murine IgA nephropathy by glomerular complement activation by aberrantly glycosylated IgA and immune complexes.

Hashimoto, Azusa; Suzuki, Yusuke; Suzuki, Hitoshi; Ohsawa, Isao; Brown, Rhubell; Hall, Stacy; Tanaka, Yuichi; Novak, Jan; Ohi, Hiroyuki; Tomino, Yasuhiko

Hashimoto, Azusa; Suzuki, Yusuke; Suzuki, Hitoshi; Ohsawa, Isao; Brown, Rhubell; Hall, Stacy; Tanaka, Yuichi; Novak, Jan; Ohi, Hiroyuki; Tomino, Yasuhiko.

Affiliation

Hashimoto A; Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.

Am J Pathol ; 181(4): 1338-47, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22871574

Subject(s)

Antigen-Antibody Complex/blood; Complement Activation/immunology; Glomerulonephritis, IGA/immunology; Glomerulonephritis, IGA/pathology; Immunoglobulin A/blood; Animals; Chromatography, Gas; Chromatography, Liquid; Female; Glomerulonephritis, IGA/blood; Glycosylation; Immunoglobulin G/blood; Kidney Glomerulus/immunology; Mannose-Binding Lectin/metabolism; Mice; Models, Immunological; Monosaccharides/metabolism; Reproducibility of Results

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin A / Complement Activation / Glomerulonephritis, IGA / Antigen-Antibody Complex Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Pathol Year: 2012 Type: Article Affiliation country: Japan

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