Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity.

Ejigiri, Ijeoma; Ragheb, Daniel R T; Pino, Paco; Coppi, Alida; Bennett, Brandy Lee; Soldati-Favre, Dominique; Sinnis, Photini

Ejigiri, Ijeoma; Ragheb, Daniel R T; Pino, Paco; Coppi, Alida; Bennett, Brandy Lee; Soldati-Favre, Dominique; Sinnis, Photini.

Affiliation

Ejigiri I; Department of Microbiology, New York University School of Medicine, New York, New York, United States of America.

PLoS Pathog ; 8(7): e1002725, 2012.

Article in En | MEDLINE | ID: mdl-22911675

Subject(s)

Malaria/parasitology; Plasmodium berghei/pathogenicity; Protozoan Proteins/metabolism; Sporozoites/physiology; Animals; Anopheles/parasitology; Cell Movement; Extracellular Matrix/parasitology; Membrane Proteins/metabolism; Mice; Mice, Inbred C57BL; Mutation; Peptide Hydrolases/metabolism; Plasmodium berghei/physiology; Protozoan Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium berghei / Protozoan Proteins / Sporozoites / Malaria Limits: Animals Language: En Journal: PLoS Pathog Year: 2012 Type: Article Affiliation country: United States

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